Thonotosassa is a medium-sized town located in the state of Florida. With a population of 15,238 people and seven associated neighborhoods, Thonotosassa is the 171st largest community in Florida.

A relatively large number of people in Thonotosassa telecommute to their jobs. Overall, about 14.19% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

The citizens of Thonotosassa are slightly better educated than the national average of 21.84% for all cities and towns, with 24.29% of adults in Thonotosassa having a bachelor's degree or advanced degree.

The per capita income in Thonotosassa in 2022 was $33,418, which is middle income relative to Florida and the nation. This equates to an annual income of $133,672 for a family of four. However, Thonotosassa contains both very wealthy and poor people as well.

Thonotosassa is an extremely ethnically-diverse town. The people who call Thonotosassa home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Thonotosassa residents report their race to be White, followed by Black or African-American. Thonotosassa also has a sizeable Hispanic population (people of Hispanic origin can be of any race). People of Hispanic or Latino origin account for 13.40% of the town’s residents. Important ancestries of people in Thonotosassa include German, Irish, English, Italian, and French.

The most common language spoken in Thonotosassa is English. Other important languages spoken here include Spanish and Arabic.