Orangeburg is a somewhat small city located in the state of South Carolina. With a population of 13,349 people and 15 associated neighborhoods, Orangeburg is the 38th largest community in South Carolina.

A relatively large number of people in Orangeburg telecommute to their jobs. Overall, about 9.04% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

In addition, Orangeburg is a college town. There are a lot of students in Orangeburg attending college, and as a result Orangeburg provides a number of services, amenities and opportunities geared to the needs and activities of students.

The percentage of people in Orangeburg who are college-educated is somewhat higher than the average US community of 21.84%: 28.52% of adults in Orangeburg have at least a bachelor's degree.

The per capita income in Orangeburg in 2022 was $19,944, which is low income relative to South Carolina and the nation. This equates to an annual income of $79,776 for a family of four. However, Orangeburg contains both very wealthy and poor people as well. Orangeburg also has one of the higher rates of people living in poverty in the nation, with 34.00% of its population below the federal poverty line.

Orangeburg is a very ethnically-diverse city. The people who call Orangeburg home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Orangeburg residents report their race to be Black or African-American, followed by White. Important ancestries of people in Orangeburg include Irish, English, Moroccan, German, and Scots-Irish.

The most common language spoken in Orangeburg is English. Other important languages spoken here include Spanish and Vietnamese.