Wytheville is a somewhat small town located in the state of Virginia. With a population of 8,177 people and three associated neighborhoods, Wytheville is the 83rd largest community in Virginia.

Telecommuters are a relatively large percentage of the workforce: 7.95% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Compared to the rest of the country, citizens of Wytheville spend much less time in their cars: on average, their commute to work is only 19.10 minutes. This also means that noise and pollution levels in the town are less than they would otherwise be.

The population of Wytheville overall has a level of education that is slightly above the US average for all US cities and towns of 21.84%. Of adults 25 and older in Wytheville, 23.46% have at least a bachelor's degree.

The per capita income in Wytheville in 2022 was $33,813, which is middle income relative to Virginia and the nation. This equates to an annual income of $135,252 for a family of four. However, Wytheville contains both very wealthy and poor people as well.

The people who call Wytheville home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Wytheville residents report their race to be White, followed by Black or African-American. Important ancestries of people in Wytheville include English, German, Irish, Scottish, and Scots-Irish.

The most common language spoken in Wytheville is English. Other important languages spoken here include Italian and Spanish.